Nowadays, USB is the most popular connection connection between PC and peripherals such as AVR programmers, printers, scanners etc. For that reason I had to modify my old serial AVR In-System-Programmer (ISP) to work with USB connection. You can say, “use a USB to Serial adaptor to connect your AVR ISP with your PC”. Yes, that could be a solution but it would cost me more money than a singe FT232BM chip because I had to include an USB to RS232 adaptor and a power supply for my programmer.